Circumstances Under Which You Should Avoid the Zopiclone Sleeping Pills

These days, almost every person on the planet experiences some “health issues.” From the smallest and insignificant (like sleeping, for example) to severe health conditions. Although this fact sounds very alarming, there is a solution for almost everything. One of the most common problems that people experience almost on a regular basis is the lack of proper sleep.

Even though some people do not consider sleep as important, it is actually a necessity. Even animals require sleep! So, if you have a problem sleeping, there is a solution for you. But, you have to make sure that you are not under one of the categories listed below as the zopiclone sleeping pills are not for everyone.

The image above is how the zopiclone molecule looks

Who should avoid zopiclone 7.5 mg?

Pregnant Women

Although some suggest that zopiclone is very harmful to women who are pregnant, plan to become pregnant, or women who are breastfeeding, that is not entirely true. This very important question was asked and answered by the Motherisk Team at the Hospital for Sick Children in Toronto and edited by Dr G. Koren, Professor of Pediatrics in Pharmacology, Ph University of Toronto and Chair in Child Health Research of the CIBC World Market Children痴 Miracle Foundation. Dr Diav-Citrin, Dr Okotore, and Ms Lucarelli are members of the Motherisk Team.

Keeping in mind that pregnant women also have sleeping problems or health issues, sleeping pills are a must in some cases. So, in order to be sure that zopiclone is not very harmful to the baby, the Motherisk team did a study specifically on pregnant women because such studies were not done before. So, the program started in 1993 and ended in 1997.

The study was called “observational cohort study” where a detailed investigation was performed in order to conclude whether or not zopiclone has the teratogenic effect. The teratogenic effect, according to the Medical Dictionary, means ” appearance of anomalies and/or developmental defects to exposure to a teratogenic agent during fetal development.”

The study was done on 40 pregnant women with different health issues or just sleeping problems. The women were divided into categories: alcohol consumption, age, cigarette smoking. One more group, called the control group, had follow-up interviews that were also similar in nature to the study group.

Both groups were similar in terms of pregnancy termination, previous miscarriages, and of course, the obvious gain weight during pregnancy. And both groups reported problems, which are illustrated in the table below:

Study Group Zopiclone Use Both Groups Reported
・ “Of the 40 pregnant women, 35 reported taking zopiclone during the first trimester and four reported taking it throughout their pregnancies.
・ Indications for zopiclone use: depression (10), insomnia (three), anxiety-depressive disorder (three), anxiety (two), bipolar disorder (two), and schizophrenia (two). Two did not know the indication, and 16 did not specify an indication.” ・ ” No differences in outcome of pregnancy, delivery method, assisted deliveries, fetal distress, presence of meconium at birth, preterm deliveries, or neonatal intensive care admissions were seen between study and control groups.
・ No significant differences were found in the rate of major or minor malformations between the two groups.
・ In each group, one infant was born with congenital hip dislocation: one required braces for 4 months ( in the control group), and one resolved after triple diapering (zopiclone).”

The final conclusion that doctors made during the cohort study are that out of the 31 newborn babies of women who have been exposed to the sleeping pills zopiclone during the first trimester is “reassuring and suggesting that the drug is not a major human teratogen.” According to the Medical Dictionary, teratogen means ” an agent or influence that causes physical defects in the developing embryo.

Although studies have proven that zopiclone is “not a major human teratogen,” it is still important to consult with your doctor first.

In the list of who should not take the sleeping pills are:

People who are allergic to the pill or any of the ingredients – some of the symptoms that were reported as allergic are fainting, coughing, swelling of the tongue, face, tongue, lips, other parts of the body, fever, itching, rash, hives on the skin. If any of those symptoms appear, consult with your doctor right away or if they get severe, you need to visit the nearest emergency room or hospital.

People who have sleep apnea. Sleep apnea is described as pauses in breathing while sleeping, and if speeling pills are taken, then the frequency of paused breathing will be increased significantly.


People who have severe breathing difficulties. People with such problems should avoid zopiclone as it will make the process of breathing even more difficult. Although not every person having such health issue gets worse, it is best to talk to your doctor first!

People who have kidney or liver disease. If you can’t tolerate certain sugars, then you must avoid zopiclone.

People who have or had mental health problems. Mental problem is a very serious condition, especially when the person with such is most likely to have suicidal thought or even attempts. When taking sleeping pills while taking other prescribed medication of mental illness, the risk of suicide increases significantly. That is why you need to talk to your doctor, list all the drugs you are taking, including herbs and over-the-counter medication.

People who have or had issues regarding any drug abuse or alcoholism. This is yet another serious problem. A case study was done in 1995-2000 by Koski et al., 2003. People who abused their medication had fetal poisoning, and people who abused alcohol had fetal toxicity indices. Poisoning from the sleeping pills, without the use of other medications, was present in 38 cases. Pathologists determined that 21 of those cases were the primary death of patients using the sleeping pills.

Although these facts are very alarming and scary, keep in mind that safety precautions must be taken at all times. In order to avoid such problems, you need to be honest with your doctor and provide a list of all medications you are currently taking and if you are suffering from other illness.

The zopiclone tablets are usually harmless and safe to take. Nonetheless, you should be always aware of any conditions you may have as even the smallest or insignificant side effect can create or worsen the condition of your current health problem. And stay with us in order to find out which medications interact with the zopiclone tablets.

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